The UPPAbaby Mesa V2 attaches straight to the UPPAbaby Vista V3; there is nothing extra to buy. With the carrier on, you are pushing about 37.5 lb (27.6 lb stroller, 9.9 lb carrier). The seat itself is rated up to 35 lb and up to 32 in, per UPPAbaby.
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32 other infant seats fit the UPPAbaby Vista V3; UPPAbaby Aria V2, UPPAbaby Mesa (original), UPPAbaby Mesa Max and 1 more need no adapter at all.
The answer is not the same on every Vista: it differs on the Vista (before 2015), as the table below shows.
Summary from the makers' published data.
How to set up the UPPAbaby Mesa V2 on the UPPAbaby Vista V3
What you need
The UPPAbaby Vista V3
The UPPAbaby Mesa V2 carrier (its car base stays in the car)
The UPPAbaby carrier attaches straight to the stroller frame; the manuals below show exactly where.
Before every walk
Check that the carrier is locked on both sides the way your manual describes. How we check our answers
Last check: give the carrier handle a gentle tug. A seat that is fully latched does not lift off.